Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps3-30-06 | Thyroid Physiology in Periphery & Development Basic | ETA2023

Development and characterization of a simple human thyroid organoid in vitro model for thyroid metabolism investigation

cristiani sofia , Bertolini Andrea , Carnicelli Vittoria , contu lucia , Chiellini Grazia , Ghelardoni Sandra , Rutigliano Grazia , Lenzi Paola , Bizzarri Ranieri

Please Development and preliminary characterization of a simple human thyroid organoid in vitro model for thyroid metabolism investigation For decades, in vitro studies of the thyroid have relied on thyroid-derived tumor cell lines, which are limited by their undifferentiated phenotype, lack of response to TSH, and chromosomal abnormalities. A viable alternative are monolayer (2D) cultures of primary thyrocytes isolated from histologically normal thyroid glan...